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Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer

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Adv Nutr 8(3):511519 Locatelli JC, Costa JG, Haynes A, Naylor LH, Fegan PG, Yeap BB et al (2024) Incretin-Based weight loss pharmacotherapy: can resistance exercise optimize changes in body composition

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While, previously, patients with severe OSA would likely require CPAP therapy for the remainder of their lives, especially as OSA tends to worsen with age and weight increase, these obesity-targeting medications offer the potential for some patients to become less dependent on CPAP or be managed using lower, more tolerable pressures. Indeed, patients on tirzepatide had about a 50% reduction in the apnea-hypopnea index and significant improvements in hypoxemia

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